Rumored Buzz on Conolidine alkaloid for chronic pain
Most recently, it's been discovered that conolidine and the above derivatives act around the atypical chemokine receptor 3 (ACKR3. Expressed in related places as classical opioid receptors, it binds to some big selection of endogenous opioids. Not like most opioid receptors, this receptor acts for a scavenger and won't activate a 2nd messenger syst